Table 2.

Reasons for which subjects did not meet the eligibility criteria, n (%)

	Polypill arm, n=812, 19.2%	Minimal care arm, n=760, 18.2%
Hypersensitivity to one of components of polypill	12(0.28)	7(0.17)
History of angioedema	1(0.02)	1(0.02)
History of gastrointestinal bleeding or peptic ulcer disease in last 3 months	13(0.31)	12(0.29)
History of stroke	37(0.87)	58(1.39)
Pregnancy or lactation	-	-
Bleeding disorders such as hemophilia	1(0.02)	1(0.02)
Regular anticoagulant use	25(0.59)	16(0.38)
Alcohol consumption	2(0.05)	1(0.02)
Advanced liver disease	25(0.59)	18(0.43)
Uncontrolled seizures	10(0.24)	14(0.34)
Severe asthma	108(2.55)	143(3.42)
History of gout	2(0.05)	1(0.02)
Serum creatinine > 2 mg/dL	27(0.64)	31(0.74)
Glomerular filtration rate < 30 ml/min	52(1.23)	64(1.53)
Hemoglobin<10 mg/dL in females and <11 mg/dL in males	210(4.96)	191(4.57)
Systolic blood pressure <90 mmHg and diastolic blood pressure < 60 mmHg	91(2.15)	37(0.89)
Medical/psychiatric comorbidities	305(7.21)	309(7.4)
Unavailability of the subjects	28(0.66)	2(0.05)

Note: Each subject may meet more than one exclusion criterion