Table 1.

Description of data provided by BRCA-Pathway: data type, data size, and data source

Data type	Data size	Data source
Clinical	1098 patients	Standardized analysis-ready TCGA
	22 attributes	data,
	1098 rows	Broad Institute TCGA genome
Expression	1093 patients	data analysis center (2016):
	20,531 genes	Firehose stddata__2016_01_28
	22,440,383 rows	run. Broad Institute of MIT and
Mutation	977 patients	Harvard.
	17,280 genes	doi:10.7908/C11G0KM9
	86,765 rows
CNV	1080 patients	Broad Institute TCGA genome
	24,776 genes	data analysis center (2016):
	26,758,080 rows	SNP6 copy number analysis (GISTIC2). Broad Institute of MIT and Harvard.doi:10.7908/C1NP23RQ
KEGG pathway	307 pathways	Kyoto encyclopedia of genes and genomes (KEGG)
Transcription factors	85,314 TF-TG pairs	Human transcriptional regulation interaction database
		(HTRIdb)
		Molecular signatures database (MSigDB)
Hallmark gene sets	50 Hallmark gene sets	Molecular signatures database (MSigDB)
Driver genes	486 driver genes	Cancer gene census in COSMIC database
		Vogelstein, Bert, et al. “Cancer genome landscapes.” science
		339.6127 (2013): 1546-1558. Table S2A