Figure 8.

Signalling to cytoskeletal mechanics and back. (a) Well‐established biochemical pathways that link signalling molecules to the cytoskeletal machinery (Reprinted with permission from Ref 181. Copyright 2012 Frontiers) (b)‐(e) are new ideas of how cytoskeletal mechanics may feedback to signalling as well. The acronyms within each box refer to key signalling molecules involved in modulating cytoskeletal components such as actin (polymerisation, turnover) and myosin (contraction). ((b) reprinted with permission from Ref 182. Copyright 2013 National Academy of Sciences; (c) reprinted with permission from Ref 183. Copyright 2017 Public Library of Science; d reprinted with permission from Ref 184. Copyright 2016 Public Library of Congress).