Figure 2.

Cdkn1c ^BACx1 animals display increased neural reactivity to an intraperitoneal injection of amphetamine associated with increased mesolimbic input cell number. Cfos expression in ventral striatum following a saline of amphetamine was significantly increased only in Cdkn1c ^BACx1 animals. Data shown is mean fold change ± SEM. *P < 0.05 main effect of DRUG. Cdkn1c ^BACx1 had significantly more Th‐positive cells than WT in VTA, but not SNc. Data shown is mean cell number per section ± SEM. *P < 0.05.