Table 1. Baseline characteristics of patients with suspected angina stratified by cardiac troponin.
| Cardiac troponin I concentrations by quintile (range [ng/L]) | |||||
|---|---|---|---|---|---|
| Q1 (≤0.82) |
Q2 (0.83-1.16) |
Q3 (1.17-1.61) |
Q4 (1.62-2.66) |
Q5 (>2.66) |
|
| n | 193 | 186 | 183 | 192 | 183 |
| Age, years | 51.8 (9.4) | 57.0 (8.3) | 59.0 (9.5) | 60.7 (8.8) | 60.7 (8.8) |
| Male, % | 60 (31.1) | 93 (50.0) | 113 (61.7) | 132 (68.8) | 135 (73.8) |
| Chest pain symptom, % | |||||
| Typical angina | 54 (28.0) | 64 (34.4) | 81 (44.3) | 101 (52.6) | 99 (54.1) |
| Atypical angina | 65 (33.7) | 39 (21.0) | 46 (25.1) | 32 (16.7) | 39 (21.3) |
| Non-anginal | 74 (38.3) | 83 (44.6) | 56 (30.6) | 59 (30.7) | 45 (24.6) |
| BMI | 29.6 (6.2) | 29.1 (5.5) | 30.1 (5.1) | 30.0 (5.5) | 29.4 (5.4) |
| Pre-existing CHD, % | 12 (6.2) | 6 (3.2) | 19 (10.4) | 20 (10.4) | 21 (11.5) |
| Hypertension, % | 36 (18.7) | 54 (29.3) | 70 (38.5) | 92 (48.7) | 84 (46.4) |
| Hyperlipidemia, % | 95 (49.2) | 109 (58.6) | 117 (63.9) | 126 (65.6) | 118 (64.5) |
| Diabetes mellitus, % | 20 (10.4) | 17 (9.1) | 13 (7.1) | 23 (12.0) | 25 (13.7) |
| Current smoker, % | 46 (23.8) | 45 (24.2) | 33 (18.0) | 31 (16.2) | 30 (16.4) |
| Family history of CHD, % | 95 (50.0) | 85 (46.4) | 81 (44.8) | 71 (37.4) | 62 (34.1) |
| 10-year CHD risk* | 11.0 [6.0, 16.0] | 15.0 [9.0, 22.8] | 17.0 [11.0, 24.0] | 19.0 [14.0, 27.0] | 19.0 [14.0, 27.5] |
Data are mean (standard deviation), median [IQR], or value (%); BMI, body mass index; CHD, coronary heart disease.
*
This value is determined through calculation of the ASSIGN Score, a risk model derived and validated within Scotland for the determination of cardiovascular risk in patients without known coronary heart disease (29)(see http://assign-score.com/)