. Author manuscript; available in PMC: 2018 Mar 5.

Published in final edited form as: Lancet Glob Health. 2017 Jan 31;5(3):e300–e309. doi: 10.1016/S2214-109X(16)30362-X

Table 1.

Key parameter values used in the estimates, and accompanying range used in the sensitivity analysis

Parameter	Symbol	Default value	Range used in sensitivity analysis	Reference(s)
HSV-2
Average number of days between HSV-2 infection and the development of protective IgG antibodies (=transmission window)	x_HSV-2	21 days	--	^19,20
Risk of neonatal infection from a prevalent maternal HSV-2 infection	r_{prev_HSV-2}	0·02%	0·0045% and 0·064%	⁷
Risk of neonatal infection from an incident maternal HSV-2 infection which occurs near labour and before antibodies have developed	r_{incid_HSV-2}	7.7%	2·7% and 15·4%	^7,17
HSV-1
Average number of days between HSV-1 infection and the development of protective IgG antibodies (=transmission window)	x_HSV-1	25 days	--	20
Risk of neonatal infection from a prevalent maternal HSV-1 infection (any HSV-1infection)	r_{prev_HSV-1}	0·0063%	0·00077% and 0·023%	⁷ and Stacy Selke, personal communication
Risk of neonatal infection from an incident maternal HSV-1 infection (any HSV-1 infection) which occurs near labour and before antibodies have developed	r_{incid_HSV-1}	11%	3·1% and 26·1%	⁷ and Amalia Magaret, personal communication, based on data described in¹⁸