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. 2018 Feb 21;14(2):e1006871. doi: 10.1371/journal.ppat.1006871

Table 2. Top differentially expressed genes in SIV+ infant macaques.

Gene Log2 F.C. Adj p-value Gene Ontology
HRASLS2 4.227 0.0368 lipid catabolism, phosphatidylethanolamine acyl-chain remodeling
ISG15 3.676 0.0082 type I interferon signaling, response to virus
IFI6 3.496 0.0002 type I interferon signaling, immune response
IFIT1B 3.492 0.0197 defense response to virus
MX1 3.458 0.0042 type I interferon signaling, response to virus, innate immune response
Saa3 3.290 0.0400 acute-phase response, I-kappaB phosphorylation, cell chemotaxis
OAS1 3.266 0.0031 type I interferon signaling, response to virus, glucose homeostasis
IFIT1 3.163 0.0079 type I interferon signaling, response to virus
SAA1 3.031 0.0370 acute-phase response, innate immune activation, macrophage chemotaxis
OASL 2.900 0.0021 type I interferon signaling, response to virus
HERC6 2.629 0.0059 protein polyubiquitination
IFIT3 2.559 0.0016 type I interferon signaling, response to virus
CMPK2 2.486 0.0048 cellular response to LPS, terminal differentiation of monocytic cells
IRF7 2.417 0.0246 regulation of type I interferon production, innate immune response, defense response to virus
EPSTI1 2.403 0.0014 nuclear translocation of NF-kappaB
OAS2 2.332 0.0025 type I interferon signaling, response to virus
H2-M2 2.308 0.00002 antigen processing and presentation via MHC class I
LBP 2.264 0.0033 acute-phase response, cellular response to LPS and lipoteichoic acid, macrophage activation
HLA-G 2.261 0.000007 antigen processing and presentation via MHC class I, regulation of tolerance induction
MX2 2.229 0.0043 type I interferon signaling, response to virus