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. 2018 Feb 21;14(2):e1006871. doi: 10.1371/journal.ppat.1006871

Table 3. Top differentially expressed genes in SIV+ ART adult macaques.

Gene Log2 F.C. Adj p-value Gene Ontology
RABIF 2.188 0.0222 protein transport, regulation of GTPase activity, membrane fusion
SH3KBP1 1.958 0.0494 apoptosis, cytoskeleton organization, cell migration
SLC22A4 1.572 0.0347 organic anion and cation transport, triglyceride metabolism, body fluid secretion
Cmah 1.565 0.0390 CMP-N-acetylneuraminate metabolism, oxidation-reduction process
CYP2F1 1.480 0.0164 xenobiotic metabolism, response to toxic substance, oxidation-reduction process
SLC2A4RG 1.446 0.0280 regulation of transcription from RNA polymerase II promoter
SECISBP2L 1.416 0.0018 selenocysteine incorporation
SYTL2 1.400 0.0347 exocytosis, intracellular protein transport, protein localization to plasma membrane
PAQR7 1.296 0.0306 response to steroid hormone, steroid hormone mediated signaling
AUTS2 1.256 0.0385 regulation of transcription from RNA polymerase II promoter
ZNF704 1.235 0.0222 regulation of transcription from RNA polymerase II promoter
FZD4 1.189 0.0359 Wnt signaling pathway, extracellular matrix-cell signaling, ubiquitin protein ligase binding
HFE2 1.152 0.0385 BMP signaling, cellular iron ion homeostasis
MTMR1 1.107 0.0347 phosphatidylinositol biosynthesis and dephosphorylation
EGFL7 1.099 0.0347 Notch signaling, cell adhesion, regulation of endothelial cell proliferation
GPC4 1.077 0.0280 Wnt signaling, cell proliferation, glycosaminoglycan metabolism
NPTX1 1.072 0.0339 chemical synaptic transmission
ROBO2 1.068 0.0280 cellular response to hormone stimulus, regulation of negative chemotaxis
PDCD6IP 1.043 0.0496 apoptosis, bicellular tight junction assembly, maintenance of epithelial cell apical/basal polarity
STXBP5 1.024 0.0397 exocytosis, protein transport, regulation of protein secretion