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. 2018 Jan 24;7:8. doi: 10.1038/s41426-017-0011-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Phylogenetic analysis of EV71, CVA16, CV-A6 and CV-A10 circulating in Shanghai in 2012-2016. a Total VP1 gene sequences from 31 EV71 strains (891 bps) in this study and 41 reference sequences downloaded from GenBank were used for phylogenetic analyses. EV71 strains circulating in Shanghai in 2012–2016 belonged to the C4a cluster. b Total VP1 gene sequences from 39 CV-A16 strains (891 bps) in this study and 22 reference sequences downloaded from GenBank were used for phylogenetic analyses. CV-A16 strains circulating in Shanghai in 2012–2016 belonged to B1a and B1b clusters. c Partial VP1 gene sequences from 38 CV-A6 strains (354 bps) in this study and 42 reference sequences downloaded from GenBank were used for phylogenetic analyses. CV-A6 strains circulating in Shanghai in 2012–2016 belonged to D-cluster 1. d Partial VP1 gene sequences from 12 CV-A10 strains (572 bps) in this study and 31 reference sequences downloaded from GenBank were used for phylogenetic analyses. CV-A10 strains circulating in Shanghai in 2012–2016 belonged to B cluster.