Table 6. Demographic, quality of life and SLE related features according to sedentary behavior.
| Parameter | Class: Time in Sedentary Behavior | Mean (SE) Model I | p>t | Mean (SE) Model II | p>t | Mean (SE) Model III | p>t |
|---|---|---|---|---|---|---|---|
| Age, years | Lowest tertiles | 44.6 (1.7) | 0.009 | ||||
| Highest tertile | 52.3 (2.3) | ||||||
| Disease Duration, years | Lowest tertiles | 9.4 (0.9) | 0.43 | ||||
| Highest tertile | 10.6 (1.2) | ||||||
| Actual SELENA-SLEDAI | Lowest tertiles | 2.3 (0.5) | <0.0001 | 2.2 (0.5) | <0.0001 | ||
| Highest tertile | 6.1 (0.7) | 6.2 (0.7) | |||||
| Number of flares, last year | Lowest tertiles | 0.25 (0.11) | 0.004 | 0.26 (0.11) | 0.008 | ||
| Highest tertile | 0.81 (0.1) | 0.80 (0.16) | |||||
| Actual SDI | Lowest tertiles | 0.45 (0.10) | 0.058 | 0.49 (0.10) | 0.19 | ||
| Highest tertile | 0.78 (0.14) | 0.72 (0.13) | |||||
| Cumulative exposure to GC, years | Lowest tertiles | 7.13 (0.9) | 0.16 | 7.5 (0.4) | 0.11 | ||
| Highest tertile | 9.2 (1.2) | 8.6 (0.6) | |||||
| Cumulative exposure to hd GC, years | Lowest tertiles | 3.3 (0.7) | 0.20 | 3.4 (0.6) | 0.27 | ||
| Highest tertile | 4.9 (1.0) | 4.6 (0.9) | |||||
| Cumulative exposure to antimalarial, years | Lowest tertiles | 5.3 (0.6) | 0.38 | 5.4 (0.5) | 0.23 | ||
| Highest tertile | 4.4 (0.7) | 4.3 (0.7) | |||||
| BDI score | Lowest tertiles | 9.8 (1.1) | 0.01 | 10.2 (1.1) | 0.07 | 11.1 (0.9) | 0.46 |
| Highest tertile | 14.6 (1.6) | 13.8 (1.6) | 12.4 (1.3) | ||||
| HAM-H score | Lowest tertiles | 11.9 (1.2) | 0.002 | 12.4 (1.2) | 0.01 | 12.9 (1.2) | 0.07 |
| Highest tertile | 18.5 (1.7) | 17.7 (1.7) | 16.6 (1.6) | ||||
| Facit-Fatigue | Lowest tertiles | 36.6 (1.3) | 0.0002 | 35.7 (1.3) | 0.001 | ||
| Highest tertile | 27.6 (1.7) | 28.4 (1.8) | |||||
| PSQI score | Lowest tertiles | 6.3 (0.6) | 0.01 | 6.5 (0.6) | 0.04 | ||
| Highest tertile | 8.7 (0.7) | 8.4 (0.7) | |||||
| SF-36 MCS | Lowest tertiles | 55.9 (2.8) | 0.012 | 55.4 (2.9) | 0.03 | 54.9 (2.7) | 0.10 |
| Highest tertile | 43.7 (3.8) | 44.6 (4.0) | 47.2 (3.7) | ||||
| SF-36 PCS | Lowest tertiles | 53.7 (2.6) | 0.0004 | 53.1 (2.6) | 0.002 | 52.7 (2.7) | 0.01 |
| Highest tertile | 37.6 (3.5) | 38.8 (3.6) | 41.1 (3.7) |
The models compares the least square mean values of variables in patients in the lower and middle tertiles of time spent in Sedentary Behavior versus patients in the upper tertile of time in Sedentary behavior. The least square means were estimated using Linear Mixed Models. Model I: an adjusted. Model II: adjusted for age and disease duration. Model III: adjusted for age, disease duration, education level and TAS score. Abbreviations: SE, standard error. MeS+, patients with MeS. MeS-, patients without MeS. GC, glucocorticoids. hd GC, high doses of glucocorticoids (daily dose ≥ 7.5 mg of prednisone or equivalents). MCS, mental component summary. PCS, physical component summary.