Table 2.
Biomarker | 50–75th percentile HR (95% CI) | 75–95th percentile HR (95% CI) | >95th percentile HR (95% CI) | Reference |
---|---|---|---|---|
TIMP-1 | 1.17 (1.05–1.30) | 1.34 (1.20–1.50) | 2.32 (1.97–2.74) | <median |
hsCRP | 1.06 (0.96–1.18) | 1.27 (1.14–1.42) | 1.29 (1.08–1.55) | <median |
MMP-9 | 0.93 (0.84–1.03) | 1.03 (0.92–1.15) | 1.02 (0.85–1.23) | <median |
Biomarker | <5 percentile HR (95% CI) | 5–25th percentile HR (95% CI) | 25–50th percentile HR (95% CI) | Reference |
eGFR | 1.42 (1.20–1.68) | 1.08 (0.96–1.20) | 0.92 (0.83–1.03) | >median |
TIMP-1, tissue inhibitor metalloproteinase-1; matrix metalloproteinase-9, MMP-9; hsCRP, high-sensitivity C-reactive protein; eGFR, estimated glomerular filtration rate; HR, hazard ratio; CI, confidence interval.