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. 2017 Aug 29;38(46):3423–3430. doi: 10.1093/eurheartj/ehx510

Table 2.

Hazard ratios from Kaplan–Meier survival analysis when categorized by percentiles

Biomarker 50–75th percentile HR (95% CI) 75–95th percentile HR (95% CI) >95th percentile HR (95% CI) Reference
TIMP-1 1.17 (1.05–1.30) 1.34 (1.20–1.50) 2.32 (1.97–2.74) <median
hsCRP 1.06 (0.96–1.18) 1.27 (1.14–1.42) 1.29 (1.08–1.55) <median
MMP-9 0.93 (0.84–1.03) 1.03 (0.92–1.15) 1.02 (0.85–1.23) <median
Biomarker <5 percentile HR (95% CI) 5–25th percentile HR (95% CI) 25–50th percentile HR (95% CI) Reference
eGFR 1.42 (1.20–1.68) 1.08 (0.96–1.20) 0.92 (0.83–1.03) >median

TIMP-1, tissue inhibitor metalloproteinase-1; matrix metalloproteinase-9, MMP-9; hsCRP, high-sensitivity C-reactive protein; eGFR, estimated glomerular filtration rate; HR, hazard ratio; CI, confidence interval.