Figure 3.

Effect of PCB126 exposure on the calcium signaling pathway. There was upregulation of several genes associated with calcium signaling in the brain of adult fish that were developmentally exposed to PCB126. These genes include voltage dependent calcium channels, glutamate and cholinergic receptors and members of downstream signaling. Genes that are differentially expressed are highlighted in green (0.3 nM PCB126), red (1.2 nM PCB126) and blue (both concentrations). (please refer to the color version of this figure online.).