Figure 4.

Effect of PCB126 exposure on oxidative phosphorylation. There was downregulation of a number of genes associated with oxidative phosphorylation in the brain of adult fish that were developmentally exposed to PCB126. These genes are associated with electron transport chain and ATP synthase. The figure shows all components of the oxidative phosphorylation pathway and the DEGs corresponding to each component are listed below. Genes that are differentially expressed are highlighted in green (0.3 nM PCB126), red (1.2 nM PCB126) and blue (both concentrations). (please refer to the color version of this figure online.)