Table 3.
Kidney allograft recipient’s demographics
| Parameter | Total (n = 44) | Immediate graft function (n = 27) | Delayed graft function (n = 17) | P-value |
|---|---|---|---|---|
| Age (years) | 42.0 ± 10.8, 41.0 (33.8, 51.3) | 43.1 ± 10.6, 44.0, (34.5, 52.0) | 43.0 ± 11.0, 39.0, (32.0, 48.0) | 0.421 |
| Gender | ||||
| Male | 27 (61.4) | 16 (59.3) | 11(64.7) | 0.761 |
| Female | 17 (38.6) | 11(40.7) | 6 (35.3) | |
| Kind of donation | ||||
| Deceased donor | 44 (100) | 27 (100) | 17 (100) | 1.000 |
| Cold ischaemia time (min) | 952.8 ± 455.3, 859.5 (609.8, 1227.0) | 803.1 ± 347.9, 720.0 (570.5, 1005.0) | 1190.6 ± 502.1, 1200.0 (794.0, 1500.0) | 0.007 |
| Maximum panel cytotoxicity (>5%) | 11 (25.0) | 7 (25.9) | 4 (23.0) | 1.000 |
| Immunosuppression—Induction therapy | ||||
| ATG Fresenius, 9 mg/kg body weight intraoperatively (i.op.) | 30 (68.2) | 19 (70.4) | 11 (64.5) | 0.124 |
| Lymphoglobulin Merieux, 30 mg/kg body weight i.op. | 11 (25.0) | 8 (29.6) | 3 (17.6) | |
| ATG Biotest, 1.5 mg/kg body weight i.op. | 1 (2.3) | 0 (0) | 1 (5.9) | |
| None | 2 (4.5) | 0 (0) | 2 (11.8) | |
| Replacement (or additional therapies) therapy after Tx | ||||
| None | 27 (61.4) | 27 (100) | 0 (0) | <0.001 |
| Haemodialysis | 16 (36.4) | 0 (0) | 16 (94.1) | |
| Peritoneal dialysis | 1 (2.3) | 0 (0) | 1 (5.9) | |
| Number of dialysis sessions | 9.1 ± 5.5 | 0 | 9.1 ± 5.5 | |
| Patient with rejection during the first year | 16 (36.4) | 8 (29.6) | 8 (47.1) | 0.337 |
| Patient with Cytomegalovirus infections during the first year | 8 (18.2) | 4 (14.8) | 4 (23.5) | 0.690 |
| Biomarker levels at day of discharge | ||||
| Day of discharge after Tx | 40.7 ± 21.3, 37.5 (23.8, 50.3) | 30.4 ± 13.2, 25.0 (20.0, 42.5) | 56.9 ± 21.5, 51.0 (38.0, 63.0) | 0.004 |
| Uromodulin (ng/mL) | 60.1 ± 43.1, 47.6 (29.3, 75.8) | 76.6 ± 45.7, 63.0 (45.0, 95.1) | 33.9 ± 19.1, 29.4 (21.2, 39.0) | <0.001 |
| Creatinine (µmol/L) | 146.0 ± 53.5, 140.0, (107.8, 170.3) | 124.7 ± 30.6, 118.0 (105.0, 145.5) | 179.8 ± 63.7, 180.0, (161.0, 191.0) | <0.001 |
| eGFR (MDRD) (mL/min) | 49.2 ± 17.0, 47.1 (36.7, 58.9) | 55.4 ± 15.5, 53.6, (44.6, 66.5) | 39.4 ± 14.5, 37.4 (32.3, 47.0) | 0.004 |
Data are presented as mean ± SD and median with IQR in brackets or as absolute numbers (n) with percentage (%) in brackets. Tx, transplantation; MDRD, Modification of Diet in Renal Disease.