Table 1.
Descriptive characteristics of gastric non-cardia adenocarcinoma (GNCA), oesophagogastric junctional adenocarcinoma (EGJA) and gastric carcinoid cases and controls from the ATBC Study
| Variable | Controls | Gastric non-cardia adenocarcinoma | aP-value | Oesophagogastric junctional adenocarcinoma | aP-value | Gastric carcinoids | aP-value |
|---|---|---|---|---|---|---|---|
| Total N | 778 | 283 | 96 | 10 | |||
| Age at baseline, mean years (SD) | 58 (5) | 58 (5) | 0.78 | 59 (5) | 0.51 | 58 (5) | 0.76 |
| Years of smoking, mean (SD) | 36 (9) | 37 (10) | 0.35 | 37 (7) | 0.12 | 38 (6) | 0.39 |
| Cigarettes/day, mean (SD) | 19 (9) | 20 (9) | 0.02 | 21 (9) | 0.03 | 18(7) | 0.69 |
| Alcohol, g/day, mean (SD) | 15 (18) | 17 (21) | 0.16 | 15 (16) | 0.97 | 24 (32) | 0.13 |
| Education: post-primary school, N (%) | 137 (18) | 27 (9) | 0.001 | 18 (19) | 0.78 | 1 (10) | 1.00 |
| BMI (kg/m2), mean (SD) | 26 (4) | 26 (4) | 0.22 | 27 (4) | 0.36 | 29 (4) | 0.04 |
| Fruit, g/day, mean (SD) | 210 (180) | 195 (154) | 0.23 | 210 (164) | 0.99 | 139 (124) | 0.22 |
| Vegetables, g/day, mean (SD) | 290 (112) | 280 (104) | 0.20 | 289 (101) | 0.93 | 283 (124) | 0.85 |
| Helicobacter pylori-positive, N (%)b | 351 (93) | 257 (99) | < 0.001 | 82 (94) | 0.76 | 8 (80) | 0.10 |
| Low pepsinogen 1 (≤ 56 ug/l), N (%)c | 10 (3) | 34 (17) | < 0.001 | 6 (9) | 0.04 | 4 (80) | < 0.001 |
aP-values from Student’s t test, Pearson’s χ2 test or Fisher’s exact test, as appropriate.
bHelicobacter pylori multiplex positivity was available for 376/778 controls, 259/283 GNCA, 87/96 EGJA and 10/10 gastric carcinoid cases.
cPepsinogen 1 data were available for 309/778 controls, 202/283 GNCA, 67/96 EGJA and 5/10 gastric carcinoid cases.