Table 3a.

Odds ratios (and 95% confidence intervals) for developing gastric cancer for those individuals by serum concentration of gastrin (continuous and quartile models)

Group	Gastrin: continuous, log				Gastrin: quartiles								Ptrend
					Q1		Q2		Q3		Q4
	OR		95% CI	P-value			OR	95% CI	OR	95% CI	OR	95% CI
Gastric cancer (n = 329)
Age-adjusted	1.24	1.06, 1.44		0.016	REF		0.84	0.57, 1.24	1.03	0.71, 1.50	1.44	1.01, 2.06	0.022
Adjusted	1.23	1.04, 1.45		0.018	REF		0.81	0.52, 1.25	1.08	0.71, 1.65	1.54	1.02, 2.32	0.022
Adj. + CCK	1.31	1.09, 1.59		0.004	REF		0.91	0.56, 1.48	1.34	0.84, 2.14	1.91	1.22, 3.01	0.001
Gastric non-cardia adenocarcinoma (n = 245)
Age-adjusted	1.29	1.08, 1.54		0.005	REF		1.03	0.66, 1.61	1.37	0.90, 2.10	1.79	1.19, 2.70	0.002
Adjusted	1.30	1.07, 1.59		0.009	REF		0.99	0.61, 1.62	1.43	0.89, 2.30	1.92	1.21, 3.05	0.002
Adj. + CCK	1.45	1.17, 1.79		0.001	REF		1.17	0.67, 2.05	1.77	1.04, 3.03	2.56	1.52, 4.30	< 0.001
Oesophagogastric junctional adenocarcinoma (n = 75)
Age-adjusted	0.82	0.61, 1.12		0.21	REF		0.47	0.24, 0.93	0.47	0.24, 0.92	0.63	0.34, 1.18	0.106
Adjusted	0.89	0.66, 1.20		0.45	REF		0.44	0.22, 0.90	0.51	0.25, 1.04	0.71	0.36, 1.39	0.106
Adj. + CCK	0.86	0.61, 1.21		0.38	REF		0.46	0.20, 1.04	0.71	0.33, 1.52	0.65	0.30, 1.44	0.415
Gastric carcinoid tumours (n = 9)
Age-adjusted	4.67	2.67, 8.15		< 0.001	REF		3.07; 1.25, 7.54						0.005

Adjusted for: age at randomization, total years of smoking and total cigarettes/day, alcohol (g/day), BMI (kg/m²), fruit intake (g/day), vegetable intake (g/day), education (post-primary school), Helicobacter pylori (+/-) and ATBC treatment group assignment; additional adjustment as indicated for CCK.

REF, reference value.