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. 2018 Jan 16;141(3):662–672. doi: 10.1093/brain/awx369

Figure 3.

Figure 3

Fibroblasts from patients show decreased levels of SCO2, COXII and copper levels. (A) Western blot shows decreased levels of SCO2 and COXII in Patients 1 and 2. One-way ANOVA with Tukey’s multiple comparisons test: control versus Patient 1 (P < 0.001), control versus Patient 2 (P < 0.01). (B) Copper levels measured by ICP-MS were significantly reduced in both patients. One-way ANOVA with Tukey’s multiple comparisons test: control versus Patient 1 (P < 0.0001), control versus Patient 2 (P < 0.0001).