. 2017 Jul 7;46(6):1751–1751g. doi: 10.1093/ije/dyx103

Box 1.

Overview of themes measured in the Doetinchem Cohort Study

Lifestyle factors: smoking (current and history), physical activity by questionnaire and Actigraph,^b sedentary time,^b alcohol consumption, sleep (hours and quality^a), chronotype.^b

Biological factors: standing height, weight, blood pressure (arm and ankle), total and HDL-cholesterol, blood glucose, (and several blood samples stored for future analyses), lung function, body mass index, waist and hip circumference, for women: reproductive history and additional characteristics on menstruation, contraception use; heel bone mass,^a accumulation of advanced glycation endproducts (AGEs) in the skin,^b urine sample (storage for future research questions).^a

Functioning: quality of life [Short Form (SF)36], cognitive functioning, hearing and eyesight issues, hand grip test,^a balance test,^a chair test.^a

Psycho-social aspects: depressive symptoms,^a loneliness,^a social support,^a health literacy,^b perception of living environment^b (in particular of possibilities for recreational physical activity).

Chronic diseases: diabetes, cardiovascular disease (claudication, stroke, heart disease), migraine, musculoskeletal pain, cancer, asthma and chronic obstructive pulmonary disease (COPD), (history of) fractures,^a list of chronic conditions (including incontinence, falling, osteoarthritis).^a

Diverse: family history of diseases (heart diseases, fractures,^a dementia,^b menopause^b), oral health^b (teeth and gums), (historical) sound pollution,^b contact with (small) children,^b consumption of tap water^b

Health care^b: use of health care services, self-management, giving and receiving informal care, acceptance of vaccination.

Background characteristics: age, sex, marital status, educational level, work status and household characteristics, (historical) shift work,^b participation^b (engagement in social activities), birthweight^b

Registry links: mortality, hospital discharge by diagnosis, cancer register and pharmacy register.

^aIncluded from round 5 (2008–12) onwards.

^bIncluded in round 6 (2013–17) additionally.