Skip to main content
. 2016 Feb 4;38(12):860–868. doi: 10.1093/eurheartj/ehw069
Choice of OAC OACs should not be used in patients where intentional non-adherence is known (i.e. choosing not to take medication)
When medication, non-adherence is unintentional (due to cognitive impairment or other impediments), strategies such as pill-boxes or engagement of a family member or caregiver to oversee administration of OAC medication should be used. NOACs may be more appropriate than VKA agents in this situation, given their fixed dose and simpler regimen
The decision of which NOAC to prescribe should not be based primarily on once vs. twice daily dosing, but this may be a factor in the decision-making process for some patients (i.e. polypharmacy, patient preference)
There is no evidence to support the use of a particular NOAC