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. 2017 May 16;158(2):401–411. doi: 10.1093/toxsci/kfx100

Figure 2.

Figure 2

PCB 11 promotes dendritic growth in primary rat hippocampal neurons. (A) Representative photomicrographs of DIV 9 hippocampal neurons after 48 h exposure to vehicle (0.1% DMSO) or varying concentrations of PCB 11. (B) Chemical structure of PCB 11. Dendritic morphology was assessed using (C) Sholl analysis and by (D) quantifying the number of primary dendrites per neuron and (E) the number of dendritic tips per neuron. Data presented as the mean ± SE (n > 70 neurons from 3 independent cultures). *P < .05, **P <.01, ***P <.001 relative to vehicle control. 1 Pixel = 0.65 micrometers.