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. 2017 May 16;158(2):401–411. doi: 10.1093/toxsci/kfx100

Figure 4.

Figure 4

Sulfated PCB 11 promotes dendritic arborization in primary cortical and hippocampal neurons. (A) Chemical structure of 4′-OSO3-PCB 11. Dendritic morphology was assessed in DIV 9 cortical (B–D) and hippocampal (E–G) neurons after 48 h exposure to vehicle (0.1% DMSO) or varying concentrations of PCB 11 sulfate using Sholl analysis (B, E) and by quantifying the number of primary dendrites per neuron (C, F) and the number of dendritic tips per neuron (D, G). Data presented as the mean ± SE (n > 70 neurons from 3 independent cultures). *P <.05, **P <.01, ***P <.001 relative to vehicle control. 1 Pixel = 0.65 micrometers.