Figure 1.

Hazard ratios of aortic valve stenosis requiring aortic valve replacement by body mass index and waist circumference. The reference group for BMI was 18.5–22.4 kg/m². For waist circumference, the reference group was <94 cm for men and <80 cm for women; increased and substantially increased waist circumference were respectively 94–101 cm and ≥102 cm for men and 80–87 cm and ≥88 cm for women. The hazard ratios were adjusted for age (time-scale), sex, education (less than high school, high school, or university), smoking status and history (never, past <10 pack-years, past ≥10 pack-years, current <10 pack-years, current 10–19 pack-years, or current ≥20 pack-years), and diabetes, hypertension, and hypercholesterolemia.