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. 2016 Nov 7;38(8):586–594. doi: 10.1093/eurheartj/ehw426

Figure 1.

Figure 1

Calibration comparing observed and predicted events in 40- to 75-year-old individuals in the Copenhagen General Population Study. US PCE performed well below 10% any atherosclerotic cardiovascular disease 10-year risk, with good calibration around the guideline-defined decision thresholds of 5% and 7.5% for statin therapy (left panel). In contrast, European SCORE overestimated risk across all deciles and categories of fatal atherosclerotic cardiovascular disease 10-year predicted risk, with substantial overestimation around both the high-risk (5%) and very-high-risk (10%) thresholds for statin therapy (right panel). Observed events were Kaplan–Meier adjusted. Error bars indicate 95% confidence interval. PCE,  pooled cohort equations; SCORE,  Systematic COronary Risk Evaluation.