Table 1.

Demographic and clinical characteristics of moderate-severe TBI patients and healthy controls

	TBI patients	Controls	Group comparison
n	61	32	–
Age, years, mean ± SD	41.55 ± 12.77	34.22 ± 10.29	P = 0.004
Sex, n, male/female	49/12	18/14	P = 0.027
Interval between scans, months, median [IQR]	13.08 [9.00–15.24]	12.72 [12.09–14.22]	P = 0.13
Scanner system, n, Philips/Siemens	36/25	13/19	P = 0.14
Time since injury, months, median [IQR]	11.71 [4.53–25.21]	–	–
Post traumatic amnesia, n (%)	56 (91.8)	–	–
Presence of focal lesions, n (%)	41 (67.2)	–	–
Presence of microbleeds, n (%)	29 (47.5)	–	–
Lowest recorded GCS score, mean ± SD	8.36 ± 4.92	–	–
Cause of injury, n
Road traffic accident	28	–	–
Violence/assault	15	–	–
Incidental fall	15	–	–
Sport	2	–	–
Unknown	1	–	–

Acute GCS scores were available in n = 28 TBI patients.

GCS = Glasgow Coma Scale; IQR = interquartile range.