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P3 neonates are resistant to BoNT/A-mediated inhibition of stimulus-EPPs. A–C, Sample records of stimulus EPPs in diaphragm NMPs of adult (2 months old), P7 and P3 neonates before and after BoNT/A (10 pM; 90 min) exposure. D, Bar graphs summarize the inhibitory effect of BoNT/A on EPPs of adult (2-month old), P7 (and older than P7) and P3 (and younger than P7) neonates. Mean ± SD for n = 8 mice; 16 NMPs and 30 endplates are given.
