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Pregnancy alters expression of Cyp450 genes in the mouse. A host of phase I and II enzyme expression was analyzed via RT-PCR. A significant reduction in expression is present in GSTA1 (p < .05), with trends of increased expression for both Cyp3A13 and Cyp3A44. Relative transcript expression was normalized to GAPDH levels. *denoted p < .05 Data shown are mean ± SEM; n = 6.
