18 weeks |
Clinical assessment: mother weight, height, doppler, ultrasound, head circumference |
Mother questionnaire: education, income, occupation, activity, stress, smoking, alcohol, caffeine, non-prescription drugs, substance exposure, medical history |
Father questionnaire: education, occupation, toxin exposure |
Mother blood sample: Vitamin D, thyroid stimulating hormone, phthalates |
34 weeks |
Mother questionnaire: life stress, caffeine, smoking, alcohol, non-prescription drugs, toxin exposure |
Mother blood sample: phthalates, thyroid stimulating hormone (stored) |
Antenatal information, maternal medical records: diabetes, hypertension, post-partum complications, labour details, placental weight and shape |
Fetus information, mother's medical records: presentation, delivery, antenatal testing |
Birth |
Neonatal assessment: weight, length, head circumference, mid-arm, chest and abdominal circumferences, skinfold thickness, dysmorphology, perinatal morbidity |
3 days post birth: mother questionnaire: postnatal blues |
Cord blood sample: cord, cytokines, androgens |
Placental sample: (stored) |