Figure 3.

Lack of correlation between selectivity (S) score and hiPSC CM beating function. Changes in beat rate (A) or amplitude (B) expressed as percent control of iPSC CM treated with 3 µM of compounds for 2 h are plotted against S score [3 µM]. All points have error bars that represent SEM from three independent experiments. The correlation of S score and effect on CM beating function was not judged to be significant for beat rate (r² = 0.008 and P = .48) or beat amplitude (r² = 0.014 and P = .34).