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. 2017 May 26;158(1):213–226. doi: 10.1093/toxsci/kfx082

Table 6.

Performance Parameters for Sentinel Kinase Model Using Clinically Tested SMKI

Entire Data Set Excluding Vascular-Mediated Hypertension
Sensitivity 0.80 0.92
Specificity 0.75 0.75
PPV 0.92 0.92
NPV 0.50 0.75
Accuracy 0.79 0.88

The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy are listed for the full set of nineteen clinically tested drugs and for the set of seventeen drugs with VEGF-targeted therapies causing hypertension excluded.