Table 3.
Pathways Enriched in All PERC-treated Groupsa
| KEGG Pathway IDb | No. of genes | Fold enrichment | Benjamini-corrected q-value |
|---|---|---|---|
| mmu00053:Ascorbate and aldarate metabolism | 4 | 13 | 3.61E−02 |
| mmu00980:Metabolism of xenobiotics by cytochrome P450 | 15 | 11 | 1.99E−09 |
| mmu01040:Biosynthesis of unsaturated fatty acids | 6 | 11 | 2.70E−03 |
| mmu00982:Drug metabolism | 16 | 10 | 1.87E−09 |
| mmu00071:Fatty acid metabolism | 9 | 9.6 | 6.56E−05 |
| mmu00830:Retinol metabolism | 13 | 9.2 | 3.42E−07 |
| mmu00590:Arachidonic acid metabolism | 13 | 7.6 | 2.63E−06 |
| mmu00480:Glutathione metabolism | 8 | 7.4 | 1.32E−03 |
| mmu03320:PPAR signaling pathway | 11 | 6.7 | 7.65E−05 |
| mmu00140:Steroid hormone biosynthesis | 6 | 6.4 | 2.68E−02 |
| mmu04610:Complement and coagulation cascades | 7 | 4.5 | 4.29E−02 |
a
As compared with diet-matched vehicle-treated animals.
b
KEGG pathways were retrieved from DAVID v 6.7, as described in the Materials and Methods section.