Table 2.
Lesion and procedural characteristics and medication
| SYNTAX II | SYNTAX I PCI arm | P-value | |
|---|---|---|---|
| Lesions anatomical syntax score per patient | 4.16±1.17 (454) | 4.31±1.34 (315) | 0.10 |
| Lesions intended to be treated per patient | 3.49±0.97 (447) | 4.60±1.55 (311) | <0.001 |
| Lesions treated per patient | 2.64±1.11 (440) | 4.02±1.34 (311) | <0.001 |
| Stents per patient | 3.78±1.92 (440) | 5.19±2.04 (308) | <0.001 |
| Stents per lesion | 1.43±0.76 (1165) | 1.28±0.65 (1251) | <0.001 |
| Vessel assessed by physiology (iFR/FFR) | |||
| Left main | 0.9% (4/447) | N/A | |
| RCA | 86.4% (386/447) | N/A | |
| LAD | 98.9% (442/447) | N/A | |
| LCX | 96.0% (429/447) | N/A | |
| Assessment in three vessels | 82.8% (370/447) | ||
| Vessel treated | |||
| Left main | 0.9% (4/441) | 2.3% (7/311) | 0.22 |
| RCA | 60.5% (267/441) | 87.1% (271/311) | <0.001 |
| LAD | 92.5% (408/441) | 99.0% (308/311) | <0.001 |
| LCX | 67.1% (296/441) | 96.5% (300/311) | <0.001 |
| Treatment in three vessels | 37.2% (164/441) | 83.3% (259/311) | <0.001 |
| Mean stent length (per stent, mm) | 24.43±9.18 (1663) | 18.82±7.04 (1599) | <0.001 |
| Total stent length (per patient, mm) | 92.32±52.78 (440) | 97.71±43.66 (308) | 0.13 |
| Bifurcation treated (%) | 35.0% (159/454) | 60.6% (191/315) | <0.001 |
| Total occlusion treated (%) | 27.8% (126/453) | 28.3% (89/315) | 0.88 |
| Post-implantation IVUS MLA (mm2) | 6.17±2.31 (1094) | N/A | |
| Medications | |||
| Aspirin | |||
| At discharge | 99.8% (448/449) | 96.2% (302/314) | <0.001 |
| At 1 month | 99.6% (443/445) | 93.9% (292/311) | <0.001 |
| At 1 year | 95.6% (413/432) | 92.1% (278/302) | 0.046 |
| P2Y12 inhibitor | |||
| At discharge | 99.3% (446/449) | 98.4% (309/314) | 0.234 |
| Clopidogrel | 66.8% (298/446) | N/A | |
| Prasugrel | 4.5% (20/446) | N/A | |
| Ticagrelor | 28.7% (128/446) | N/A | |
| At 1 month | 99.6% (443/445) | 97.1% (302/311) | 0.004 |
| Clopidogrel | 66.8% (298/446) | N/A | |
| Prasugrel | 4.5% (20/446) | N/A | |
| Ticagrelor | 28.7% (128/446) | N/A | |
| At 1 year DAPT | 61.8% (267/432) | 72.2% (218/302) | 0.0034 |
| Beta-blocker at discharge | 75.7% (339/448) | 77.1% (242/314) | 0.66 |
| Statin at discharge | 97.3% (437/449) | 85.4% (268/314) | <0.001 |
DAPT, dual antiplatelet therapy; IVUS, intravascular ultrasound; FFR, fractional flow reserve; iFR, Instantaneous wave-free ratio; MLA, minimum lumen area; LAD, left anterior descending artery; LCX, left circumflex; RCA, right coronary artery.