FIG. 7.

Mercury body burden with GSTP1 expression. Larvae carrying GSTP1_wt, GSTP1₁₀₅, GSTP1₁₁₄ expression, or control larvae, were reared on the indicated concentrations of MeHg food. For each treatment a single determination of a pooled sample of 10 pupae was analyzed for total mercury (Hg (ppm)). Numbers above bars indicate the percent change in Hg in each of the GSTP1 variant pupae compared with the respective control pupae for each MeHg treatment. Significant decrease in Hg body burden across MeHg treatments was seen for FB > GSTP1₁₁₄ [95% CI (−34% to − 2% below control), P = .041, P = .123 multiple comparison protected], NP1 > GSTP1₁₁₄ [95% CI (−11% to − 6% below control), P = .004, P = .012 multiple comparison protected] and NP1 > GSTP1₁₀₅ [95% CI (−3% to − 0.2% below control), P = .038, P = .114 multiple comparison protected]. See Results section text for additional statistics.