Table 1.
Demographic, anthropometric and laboratory characteristics of the study population
| 1998–2003 | 2004–09 | 2010–15 | ||||
|---|---|---|---|---|---|---|
| (n = 1164) | (n = 1261) | (n = 1312) | Trend test 1 | Trend test 2 | Trend test 3 | |
| P-value | P-value | P-value | ||||
| Height (cm) | 170.6 ± 5.6 | 170.9 ± 5.5 | 170.6 ± 5.7 | 0.99 | 0.52 | 0.99 |
| Weight (kg) | 60.3 ± 8.3 | 60.9 ± 8.7 | 60.5 ± 8.6 | 0.49 | 0.15 | 0.87 |
| BMI (kg/m2) | 20.7 ± 2.5 | 20.8 ± 2.6 | 20.8 ± 2.5 | 0.52 | 0.24 | 0.94 |
| SBP (mmHg) | 114.8 ± 12.6 | 116.9 ± 13.4 | 113.9 ± 12.9 | 0.07 | 0.20 | 0.07 |
| DBP (mmHg) | 61.5 ± 8.2 | 65.9 ± 9.1 | 63.1 ± 9.7 | <0.01 | <0.01 | <0.01 |
| Mean BP (mmHg) | 79.2 ± 8.2 | 82.8 ± 9.9 | 80.0 ± 9.8 | 0.047 | <0.01 | 0.04 |
| Cr (mg/dL) | 0.75 ± 0.10 | 0.79 ± 0.10 | 0.81 ± 0.10 | <0.01 | <0.01 | <0.01 |
| eGFR (mL/min) | 105.1 ± 15.9 | 99.7 ± 14.1 | 97.4 ± 13.8 | <0.01 | <0.01 | <0.01 |
| TC (mg/dL) | 169.7 ± 27.6 | 167.3 ± 27.1 | 167.2 ± 26.8 | 0.03 | 0.01 | 0.17 |
| TG (mg/dL)a | 49.0 (36.0–66.0) | 52.0 (39.0–75.0) | 56.0 (41.0–80.0) | <0.01 | <0.01 | <0.01 |
| High-density lipoprotein (mg/dL) | 63.3 ± 13.2 | 65.8 ± 13.4 | 62.6 ± 11.6 | 0.21 | 0.04 | <0.01 |
| UA (mg/dL) | 6.1 ± 1.2 | 5.9 ± 1.1 | 5.9 ± 1.1 | <0.01 | <0.01 | <0.01 |
| Glucose (mg/dL) | 88.7 ± 6.5 | 84.8 ± 9.4 | 86.0 ± 7.2 | <0.01 | <0.01 | <0.01 |
| Birth weight (g) | 3213.4 ± 383.8 | 3170.6 ± 382.7 | 3116.2 ± 382.3 | <0.01 | <0.01 | <0.01 |
| Gestational age (wk) | 39.1 ± 1.5 | 39.1 ± 1.6 | 39.0 ± 1.4 | 0.25 | 0.29 | 0.50 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate. Values are expressed as mean ± SD.
Trend test 1: a trend test with a linear contrast between three time periods; trend test 2: a trend test with a contrast showing a plateau at a middle category between three time periods; trend test 3: linear trend across years.
a
TG values are expressed as median (IQR).