Table 2.
Percentage of CRT implants with ICD (CRT-D), stratified by sex
% CRT-D |
|||
---|---|---|---|
Female | Male | Difference, % (95% CI)a | |
(n = 73 822) | (n = 194 016) | ||
Overall | 80.1 | 88.6 | 8.5 (7.6–9.4) |
Age | |||
< 80 years | 85.3 | 91.4 | 6.2 (5.3–7.0) |
≥ 80 years | 63.2 | 79.0 | 15.8 (14.0–17.6) |
Type of admission | |||
Elective | 82.3 | 89.7 | 7.4 (6.3–8.6) |
Acute | 77.9 | 87.6 | 9.7 (8.4–10.9) |
Cardiac history | |||
Ventricular arrhythmia | 92.7 | 95.6 | 2.9 (2.0–3.9) |
Non-ischaemic cardiomyopathy | 86.5 | 90.3 | 3.8 (3.0–4.7) |
Left bundle branch block | 88.8 | 91.8 | 3.0 (2.2–3.9) |
Atrial fibrillation | 65.5 | 84.0 | 18.6 (17.0–20.3) |
Complete AV block | 59.1 | 73.8 | 14.6 (11.9–17.4) |
Chronic kidney disease | 78.0 | 87.9 | 10.0 (8.4–11.5) |
Reduced ICD Efficacyb | |||
0 | 85.5 | 87.8 | 2.4 (0.6–4.1) |
1–2 | 79.2 | 88.7 | 9.5 (8.3–10.7) |
≥3 | 79.1 | 88.7 | 9.6 (8.3–10.7) |
CRT response variablesc | |||
0 | 59.4 | 83.6 | 24.2 (19.9–28.6) |
1–2 | 71.6 | 86.8 | 15.2 (13.8–16.7) |
≥3 | 90.5 | 92.8 | 2.3 (1.6–3.1) |
All comparisons between female and age male had P < 0.05.
Comprised of seven comorbidities associated with increased mortality and reduced ICD efficacy in patients with heart failure: ischaemic heart disease, atrial fibrillation, diabetes mellitus, chronic lung disease, chronic kidney disease, peripheral vascular disease, and smoking.
Comprised of four conditions associated with an increased likelihood of left ventricular reverse remodeling following CRT: non-ischaemic cardiomyopathy, left bundle block, absence of chronic kidney disease, and absence of atrial fibrillation.