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. 2017 Jan 8;38(19):1485–1494. doi: 10.1093/eurheartj/ehw598

Table 2.

Percentage of CRT implants with ICD  (CRT-D), stratified by sex

% CRT-D
Female Male Difference, %  (95% CI)a
(n = 73 822) (n = 194 016)
Overall 80.1 88.6 8.5  (7.6–9.4)
Age
 < 80 years 85.3 91.4 6.2  (5.3–7.0)
 ≥ 80 years 63.2 79.0 15.8  (14.0–17.6)
Type of admission
 Elective 82.3 89.7 7.4  (6.3–8.6)
 Acute 77.9 87.6 9.7  (8.4–10.9)
Cardiac history
 Ventricular arrhythmia 92.7 95.6 2.9  (2.0–3.9)
 Non-ischaemic cardiomyopathy 86.5 90.3 3.8  (3.0–4.7)
 Left bundle branch block 88.8 91.8 3.0  (2.2–3.9)
 Atrial fibrillation 65.5 84.0 18.6  (17.0–20.3)
 Complete AV block 59.1 73.8 14.6  (11.9–17.4)
Chronic kidney disease 78.0 87.9 10.0  (8.4–11.5)
Reduced ICD Efficacyb
 0 85.5 87.8 2.4  (0.6–4.1)
 1–2 79.2 88.7 9.5  (8.3–10.7)
 ≥3 79.1 88.7 9.6  (8.3–10.7)
CRT response variablesc
 0 59.4 83.6 24.2  (19.9–28.6)
 1–2 71.6 86.8 15.2  (13.8–16.7)
 ≥3 90.5 92.8 2.3  (1.6–3.1)
a

All comparisons between female and age male had P < 0.05.

b

Comprised of seven comorbidities associated with increased mortality and reduced ICD efficacy in patients with heart failure: ischaemic heart disease, atrial fibrillation, diabetes mellitus, chronic lung disease, chronic kidney disease, peripheral vascular disease, and smoking.

c

Comprised of four conditions associated with an increased likelihood of left ventricular reverse remodeling following CRT: non-ischaemic cardiomyopathy, left bundle block, absence of chronic kidney disease, and absence of atrial fibrillation.