Table 2.
Potency of C-DEP and Fractions in the Zebrafish Locomotor Assay
| Sample | Potency/Slopesa | r2 | P-Value* |
|---|---|---|---|
| C-DEP | 2.43 | 0.224 | < .0001 |
| F1 | 0.11 | 0.036 | .0024 |
| F2 | 4.96b | 0.175 | < .0001 |
| F3 | 11.35c | 0.169 | < .0001 |
| F4 | 1.79 | 0.237 | < .0001 |
a
Data are slopes of linear regressions of dose-response data.
b
The difference in potency between F2 and F1 approached statistical significance (P = .18).
c
Potency of F3 statistically greater than potency of C-DEP (P = .02), F1 (P = .01), and F4 (P = .02) and nearly F2 (P = .07).
*
Indicate P-values of linear regressions.