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Size and surface charge of PEG-PLGA NPs encapsulating DOX, formulated with DMAB as the emulsion stabilizer (n=3 replicate formulations; mean ± st. dev)
| 1% DMAB PEG-PLGA | Size (nm) | Charge (mV) | DOX Encapsulation (%) |
|---|---|---|---|
| 0% w/w DOX | 254.5 ± 36.8 | 24.2 ± 2.4 | N/A |
| 2% w/w DOX | 246.1 ± 4.4 | 21.8 ± 3.0 | 72.95 ± 4.5 |
| 5% w/w DOX | 285.9 ± 14.9 | 25.1 ± 2.0 | 82.11 ± 1.0 |
| 10% w/w DOX | 269.8 ± 31.7 | 23.5 ± 5.8 | 87.42 ± 2.3 |
