Table 2.

Quantitative electroencephalographic (qEEG) characteristics before and after sedation interruption

Parameter	Pre-interruption	Post-interruption	Change	P value for change
aEEG (uV)	6.6 [2.7 – 10.4]	9.3 [4.1 – 14.8]	1.1 [0.09 – 4.0]	0.002
SR (%)	0 [0 – 20]	0 [0 – 8]	0 [−7 – 0]	<0.001
ADR	0.60 [0.41 – 0.97]	0.72 [0.41 – 1.15]	0.03 [−0.08 – 0.19]	0.1

Data are presented as medians with interquartile ranges. P values are for the paired t-test that post-interruption values equal pre-interruption values.

Note: Although the distributions of the pre- and post-interruption data are not normally distributed, the differences are normal, meeting the assumption of the parametric t-test. Median SR values were zero due to several subjects’ EEGs having a baseline reactivity above the suppression cutoff threshold (see discussion).