Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(a) Time series of RMSDs of protein CA atoms during the 100 ns simulation in PRMT5-SAM-T1551 and PRMT5-SAM-EPZ015666 systems. (b) Crystal structure of PRMT5-SAM-EPZ015666 (PDBID: 4X61). The binding modes of PRMT5 with (c) T1551 and (d) EPZ015666. Both two complex structures were extracted from the last equilibrated 20 ns trajectory by clustering analysis.
