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. 2018 Mar 5;8:3993. doi: 10.1038/s41598-018-22148-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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sRNA_Seq results. Smear plots for control vs KOC (A), BMFC (C) and KOC + BMFC (B) groups. (D) Venn diagram of differentially expressed miRNAs. (E) Validation of selected miRNAs. Values are means ± SEM. Statistically significant difference vs control at *p < 0.05–0.005; **p < 0.005–0.0005; ***p < 0.0005. BMFC: buttermilk fat concentrate rich in phospho- and sphingolipids; KOC: krill oil concentrate rich in omega-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid) and phospholipids; BMFC + KOC: combination of BMFC and KOC.