Fig. 2.

Persistence of GFP⁺ fibroblast-like cells at late remodeling phase post-wounding. a Conversion of wound-site macrophages (GFP⁺ green) to fibroblast-like cells was abundant, particularly closer to newly forming epidermis, at the early phase (d5). Wound edge shown in yellow arrow head, scale bar = 200 µm. b, c Such cells of myeloid origin (GFP⁺ green) were observed to be present throughout granulation tissue in later phases d35 and d56. Wound edge shown in yellow arrow head, scale bar = 200 µm. d, e FSP1 (blue) immunostaining of d35 and d56 wounds from LysM^CreRosa^mT/mG mice. Colocalization of FSP1 with GFP⁺ cells, n = 5, scale bar = 10 µm