Table 2.

General treatment prediction (HAM-D remission)

Region (BA)	Step 1: Significant prediction effects							Step 2: Follow-up comparisons
	FWE-Corr (Cluster)	Cluster size (# of voxels)	x	y	z	Z score (Peak)	Cohen’s da (Cluster)	Pretreatment comparison to controls (Cluster)	Change from pretreatment to posttreatment (Cluster)
Remitters>non-remitters
ACC/mPFC (BA 24)-L	0.000	2880	−4	32	6	4.52	R>NR d = 1.16	NR<C: p = 0.000, d = 1.22 R = C: p = 0.943, d = 0.02	NR: Pre>Post, p = 0.006 R: Pre = Post, p = 0.832 C: Pre = Post, p = 0.486

Columns under step 1 are referring to voxel-wise results from a whole-brain fMRI analysis using a family-wise error corrected p-value for clusters at alpha p < 0.001 cluster extent threshold. Columns under Step 2 are referring to the statistics calculated on the extracted beta estimates from the clusters identified in Step 1

Bold values denote significant effects

FWE-Corr SPM8 family-wise error corrected p-value for clusters at alpha p < 0.001 correcting for multiple comparisons, cluster size the number of voxels within the cluster that survived threshold, x, y, z coordinates in MNI space of the peak voxel identified in the cluster, Z score the Z score of the peak voxel within the cluster, Cohen’s d for the extracted beta coefficients of the full cluster identified in the voxel wise analysis, BA Brodmann’s area; L left, ACC anterior cingulate cortex, mPFC medial prefrontal cortex, R remitters, NR non-remitters, C controls

^aControlling for age, duration of depressive episode, and baseline depression severity