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. 2018 Mar 5;8:3973. doi: 10.1038/s41598-018-22462-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The support parameters of paw and hind limb were improved in PD with exercise animal. (A) Print length, (C) intermediate toe spread and (D) foot angle data revealed impairments were ameliorated after exercise in PD animals. However, (B) toe spread length was similar between groups. (E) The data from support parameters of each group from post-lesion 2nd to 5th weeks were averaged and plotted. (PL: print length, TS: Toe spread, IT: Intermediate toe spread, Ft Ang: Foot angle).