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. 2018 Feb 9;8(4):343–349. doi: 10.3892/br.2018.1061

Table V.

Relationship between KIF3A expression and clinicopathological parameters in the140 cases by intensity of positive.

Intensity of positive

Item 0 1 2 3 No. P-value
Age 0.728
  ≤53 2 15 31 32   80
  >53 2   7 25 26   60
Pathology grade 0.000b
  I 1   7   4   0   12
  I–II 0   2 12   8   22
  II   2 13 37 43   95
  III   0   0   2   5   7
ER
  Positive 2 12 35 39   88 0.463
  Negative 1 10 16 15   42
PR
  Positive 2 10 32 34   78 0.475
  Negative 0 11 20 20   51
AR
  Positive 4 12 36 48 100 0.021a
  Negative 0 10 20 10   40
HER2
  Positive 1   5 13 23   42 0.211
  Negative 2 17 38 32   89
Lymph node
metastasis
  TnN0 4   4 23 37   86 0.013a
  TnNn 0 18 21 16   46
P53
  Positive 1 15 33 37   86 0.495
  Negative 2   7 21 16   46
Ki-67
  − 1   6 11   6   24 0.320
  + 2 11 32 30   75
  ++ 0   4   7 11   22
  +++ 0   1   3   6   10
Ck56
  Positive 0   2 10   7   19 0.757
  Negative 3 20 43 46 112
EGFR
  Positive 4 19 43 36 102 0.023a
  Negative 0   3 13 21   37
TN
  TNBC 0   6   5   7   18 0.046
  NTNBC 6 23 43 31 103
a

P<0.05

b

P<0.001. KIF3A, Kinesin Family Member 3A; ER, estrogen receptor; PR, progesterone receptor; AR, androgen receptor; HER2, human epidermal growth factor receptor 2; EGFR, epidermal growth factor receptor; TN, triple-negative; TNBC, triple-negative breast cancer; NTNBC, non-triple-negative breast cancer.