Skip to main content
. 2018 Feb 9;8(4):343–349. doi: 10.3892/br.2018.1061

Table VII.

Relationship between KIF3A expression and clinical pathological parameters in the140 cases by final score.

Final score

Item 0 1 2 3 No. P-value
Age 0.465
  ≤53 6 18 26 30   80
  >53 2 14 26 18   60
Pathology grade 0.001a
  G I 3   6   3   0   12
  G I–II 0   4 13   5   22
  G II 4 21 32 38   95
  G III 0   1   3   3   7
ER 0.008a
  Positive 5 15 39 24   83
  Negative 2 15   9 21   47
PR 0.135
  Positive 3 10 29 20   62
  Negative 2 20 20 25   67
AR 0.309
  Positive 7 19 37 37 100
  Negative 1 13 15 11   40
HER2 0.344
  Positive 2   7 14 19   42
  Negative 5 23 35 26   89
Lymph node metastases 0.218a
  TnN0 5   8 21 20   54
  TnNn 3 23 31 27   84
P53 0.125
  Positive 2 22 29 33   86
  Negative 5   9 19 13   46
Ki-67 0.023a
  − 2   6 10   6   24
  + 4 19 29 23   75
  ++ 1   3   8 10   22
  +++ 0   2   1   7   10
Ck56 0.872
  Positive 0   4   8   7   19
  Negative 7 26 40 39 112
EGFR 0.054
  Positive 6 28 38 30 102
  Negative 2   4 14 17   37
TN 0.873
  TNBC 0   3   8   7   18
  NTNBC 3 17 43 40 103
a

P<0.05

b

P<0.001. KIF3A, Kinesin Family Member 3A; ER, estrogen receptor; PR, progesterone receptor; AR, androgen receptor; HER2, human epidermal growth factor receptor 2; EGFR, epidermal growth factor receptor; TN, triple-negative; TNBC, triple-negative breast cancer; NTNBC, non-triple-negative breast cancer.