Table 1.
Top biological process GO terms associated with the DEGs identified by comparing the DON and ZEN mycotoxin treatment groups with the control group
| Name | GOID1) | Term2) | Count3) | Genes4) | p-value |
|---|---|---|---|---|---|
| biological_process | GO:0002376 | Immune system process | 8 | SLC7A2, CD207, UBD, LOC100622791, SLA-7, ORM1, IGFBP2, IGF1 | 0.003 |
| biological_process | GO:1901575 | Organic substance catabolic process | 7 | SDS, OAT, UBD, CCRN4L, LOC100525856, TRHDE, IGF1 | 0.005 |
| biological_process | GO:0044248 | Cellular catabolic process | 7 | SDS, OAT, UBD, CCRN4L, LOC100525856, TRHDE, IGF1 | 0.005 |
| biological_process | GO:0044281 | Small molecule metabolic process | 7 | CA2, SDS, OAT, GPT2, FAXDC2, IGF1, HMGCS2 | 0.011 |
| biological_process | GO:0019752 | Carboxylic acid metabolic process | 5 | SDS, OAT, GPT2, FAXDC2, IGF1 | 0.012 |
| biological_process | GO:0009056 | Catabolic process | 7 | SDS, OAT, UBD, CCRN4L, LOC100525856, TRHDE, IGF1. | 0.013 |
| biological_process | GO:0050896 | Response to stimulus | 17 | SLC7A2, CD207, CA2, UBD, CCRN4L, LOC100515475, GAS1, LOC100525856, TRHDE, ARHGEF6, LOC100622791, SLA-7, GALP, IGFBP2, MT1A, IGF1, ADORA3 | 0.013 |
| biological_process | GO:0023051 | Regulation of signaling | 7 | CA2, UBD, GAS1, LOC100525856, ARHGEF6, IGFBP2, IGF1 | 0.049 |
| biological_process | GO:0043436 | Oxoacid metabolic process | 5 | SDS, OAT, GPT2, FAXDC2, IGF1 | 0.015 |
| biological_process | GO:0006082 | Organic acid metabolic process | 5 | SDS, OAT, GPT2, FAXDC2, IGF1 | 0.016 |
| biological_process | GO:1901605 | Alpha-amino acid metabolic process | 3 | SDS, OAT, GPT2 | 0.023 |
| biological_process | GO:1901565 | Organonitrogen compound catabolic process | 3 | SDS, OAT, TRHDE | 0.024 |
| biological_process | GO:0042104 | Positive regulation of activated T cell proliferation | 2 | IGFBP2, IGF1 | 0.025 |
| biological_process | GO:0045321 | Leukocyte activation | 4 | SLC7A2, UBD, IGFBP2, IGF1 | 0.026 |
| biological_process | GO:0043567 | Regulation of insulin-like growth factor receptor signaling pathway | 2 | IGFBP2, IGF1 | 0.028 |
| biological_process | GO:0001775 | Cell activation | 4 | SLC7A2, UBD, IGFBP2, IGF1 | 0.041 |
| biological_process | GO:0006520 | Cellular amino acid metabolic process | 3 | SDS, OAT, GPT2 | 0.046 |
GO, gene ontology; DEGs, differentially expressed genes; DON, deoxynivalenol; ZEN, zerolenone.
1)
Gene ontology ID of the biological process.
2)
Name of the biological term.
3)
Number of significant genes which are involved in biological terms.
4)
Name of the genes which are involved in the particular biological term.