Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
a) RON tyrosine kinase receptor structure; highlighted are the two somatic mutations detected in brain secondary lesions from lung cancers (R1136C and P1162S) and R1335G polymorphism (NCBI rs1062633). b) Details on somatic mutations and recurrent single nucleotide polymorphism (SNP). c) Bioinformatics prediction of pathogenic role of the changes found. IPT: immunoglobulin-plexin-transcription; PM: plasma membrane; SEMA: semaphorin; TK: tyrosine kinase.
