Table 3.
Summary of the characteristics of five T‐cell receptor–peptide–MHC (TCR‐pMHCs). Interface areas, change of fluctuations in CDR3α and CDR3β, and correlativity of the fluctuations
| TCR | Interface areas (Å2) (T‐pM/T‐M/T‐p)a | Change in fluctuations from the free to complex states | Correlativity of fluctuations between CDR3α and CDR3β | |||
|---|---|---|---|---|---|---|
| Crystal structures | MD (average) | CDR3α | CDR3β | Free state | Complex | |
| B3K506 | 1163/932/455 | 1230/998/456 | Decrease | Decrease | Non‐correlative | Correlative |
| 14.C6 | 1033/822/382 | 1126/903/385 | Decrease | Decrease | Non‐correlative | Correlative |
| J809.B5 | 836/635/343 | 1047/850/339 | Decrease | Decrease | Non‐correlative | Correlative |
| 2W20 | 992/787/396 | 923/716/329 | Not decrease | Not decrease | Non‐correlative | Correlative |
| YAe62 | 760/596/304 | 857/739/218 | Not decrease | Not decrease | Correlative | Non‐correlative |
a
T, TCR; pM, peptide‐MHC; M, MHC; p, peptide.