Table 4. Comparison of Mother-Offspring and Father-Offspring Tetrachoric Correlations for MD Across Major Family Types.
| Family Type by Source of Resemblance | Tetrachoric Correlation (95% CI) | Uncorrected P Value for Test of Heterogeneity | ||
|---|---|---|---|---|
| Mothers | Fathers | Weighted Estimate | ||
| Intact | ||||
| Gene + rearing | 0.18 (0.18-0.19) | 0.15 (0.15-0.16) | 0.17 (0.16-0.17) | <.001a |
| NLW father | ||||
| Gene + rearing | 0.18 (0.17-0.19) | NA | 0.18 (0.17-0.19) | NA |
| Genes only | 0.09 (0.07-0.10) | 0.09 (0.07-0.10) | NA | |
| Stepfamilies | ||||
| Gene + rearing | 0.18 (0.17-0.20) | NA | 0.18 (0.17-0.20) | NA |
| Rearing only | NA | 0.09 (0.07-0.11) | 0.09 (0.07-0.11) | NA |
| Adoptive | ||||
| Genes only | 0.05 (0.01-0.09) | 0.05 (-0.01-0.11) | 0.05 (0.02-0.08) | .96 |
| Rearing only | 0.08 (0.04-0.11) | 0.05 (0.00-0.10) | 0.07 (0.04-0.10) | .40 |
| Weighted estimate across all family types | ||||
| Gene + rearing | 0.18 (0.18-0.18) | 0.15 (0.15-0.16) | 0.17 (0.16-0.17) | <.001 |
| Genes only | 0.05 (0.01-0.09) | 0.08 (0.07-0.10) | 0.08 (0.06-0.09) | .02 |
| Rearing only | 0.08 (0.04-0.11) | 0.08 (0.06-0.10) | 0.08 (0.07-0.09) | .99 |
Abbreviations: MD, major depression; NA, not applicable; NLW, not-lived-with.
a
Significance threshold after Bonferroni correction for 5 tests was P < .01.