Table 2. Associations Between VA and Retinal Morphological Features of DME and DRa.
| Variable | VA, Mean (SD), Letters |
B (95% CI) | P Value |
|---|---|---|---|
| Shape of DME | |||
| Dome | 54.7 (14.4) | −1.7 (−9.1 to 5.5) | .62 |
| Fusiform | 56.9 (15.3) | 1 [Reference] | |
| Septae in cystoid abnormalities | |||
| Yes | 57.1 (13.5) | 1 [Reference] | .19 |
| No | 49.9 (15.0) | −4.7 (−11.9 to 2.4) | |
| DRIL | |||
| Yes | 46.1 (14.9) | 1 [Reference] | <.001b |
| No | 58.1 (13.5) | 9.8 (3.0 to 16.6) | |
| ELM disrupted | |||
| Yes | 46.1 (14.8) | 1 [Reference] | <.001b |
| No | 61.0 (11.5) | 13.9 (7.9 to 19.8) | |
| EZ disrupted | |||
| Yes | 48.2 (14.8) | 1 [Reference] | .001b |
| No | 60.6 (12.4) | 10.5 (4.7 to 16.4) | |
| DR severity stage | |||
| Mild NPDR | 59.9 (14.0) | 11.6 (2.0 to 21.1) | .01b |
| Moderate NPDR | 55.0 (14.6) | 8.8 (−1.0 to 18.7) | .07 |
| PDR | 45.1 (14.2) | 1 [Reference] |
Abbreviations: ELM, external limiting membrane; EZ, ellipsoid zone; DME, diabetic macula edema; DR, diabetic retinopathy; DRIL, disorganization of inner retinal layers; NPDR, nonproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy; VA, visual acuity.
a
Results are reported from general linear regression model adjusted for retinal thickness at fovea.
b
Statistically significant (P < .05).