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USP8 variants in corticotroph adenomas identified by Sanger sequencing. Sanger sequences of pituitary adenomas demonstrate USP8 variants in six tumors. Encoded protein sequences are shown in one-letter code, with mutant amino acids in red. The variant in HYP29 appears to be homozygous or hemizygous. Reverse sequence is shown as reverse complement. Fwd, forward; rev, reverse.
